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Because some can cause serious side effects or interact with other medications you are taking, be sure to let your doctor know all the medications you take.

Your doctor can guide you to the right antihistamine for you.

That means you can control your symptoms with only 1 or 2 doses each day compared with older medications, which usually require doses every 4 to 6 hours to maintain their effectiveness.

Other common OTC brands that include the antihistamine diphenhydramine include: Chlorpheniramine is the main active ingredient in Chlor-Trimeton.

It helps relieve runny nose, sneezing, itchy or watery eyes, and nose and throat itching from hay fever. It comes in an immediate-release tablet, an extended-release tablet, a chewable tablet, a lozenge, a capsule, and a liquid.

Loratadine is also the main active ingredient in these other OTC brands: Fexofenadine is the main active ingredient in Allegra.

It helps relieve runny nose, sneezing, itchy and watery eyes, and itching of the nose or throat due to hay fever or other upper respiratory allergies.

When you have an allergic reaction, your body releases a substance called histamine.

Histamine causes allergy symptoms when it binds to receptors on certain cells in your body.

It comes in a tablet, a chewable tablet, a tablet that dissolves in your mouth, a capsule, a liquid-filled capsule, and a liquid.

Benadryl also comes in topical forms, such as creams, gels, and sprays, to treat allergic skin conditions such as hives.

Zyrtec can also be used to help relieve redness and itching due to hives.

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